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Single-cell machine learning uncovers genetically anchored, cell-type specific programs of Alzheimer’s disease
The work applies single-cell machine learning to identify programs associated with Alzheimer’s disease that are specific to particular cell types and genetically anchored.
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Single-cell machine learning uncovers genetically anchored, cell-type specific programs of Alzheimer’s disease Nature
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Mapping Alzheimer’s-related programs to specific cell types can make disease biology more precise than broad tissue-level patterns. Their genetic anchoring may also help connect cellular activity with inherited risk.
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